Associate Director, Gene Therapy Viral Technologies

Auris Health

Auris Health

United States
Posted on Friday, April 28, 2023


Janssen Research & Development, LLC, a member of Johnson & Johnson's Family of Companies, is recruiting for an Associate Director, Gene Therapy Viral Technologies, located in Spring House, PA.

At the Janssen Pharmaceutical Companies of Johnson & Johnson, what matters most is helping people live full and healthy lives. We focus on treating, curing and preventing some of the most devastating and complex diseases of our time. And we pursue the most promising science, wherever it might be found.

Janssen Research & Development, LLC discovers and develops innovative medical solutions to address important unmet medical needs in oncology, immunology, neuroscience, infectious diseases and vaccines, cardiovascular and metabolism, and pulmonary hypertension. Please visit http://www.janssenrnd.com for more information.

The Associate Director, Gene Therapy Viral Technologies position in the RNA, Gene Therapy and Delivery Department of Janssen Therapeutics Discovery offers an exciting opportunity to help develop novel Gene Therapies for unmet medical needs. We are investigating the use of Adeno-Associated Virus (AAV) vectors to deliver therapeutic proteins to patients for disease prevention and treatment, especially for ophthalmological, neurological, and novel therapies for infectious disease.

We are seeking a highly motivated and independent researcher to lead the group that is actively testing and developing technologies to expand gene therapies to common diseases with millions of patients. The manufacturing challenge requires innovations in engineering viruses and the cell lines used to produce them. Increased virus potency and altered tropism will be necessary to develop effective treatments for some diseases. This individual will play an important role in meeting these challenges and bringing innovative therapies to patients.

Principal Responsibilities:

  • Lead a discovery research team developing innovative ways to produce viral vectors for Gene and Cell therapies at large scale through cellular- and virus-engineering, modulation of antiviral defenses, and inducible technologies.
  • Subject matter expert in AAV biology and viral manufacturing.
  • Stay ahead of the AAV gene therapy field by identifying new technologies outside the company and collaborating to critically evaluate these technologies for potential in-licensing or acquisition.
  • Closely mentor scientists to further develop talent within the group.
  • Execute research timelines to meet program and corporate objectives.
  • Foster a collaborative and creative culture of scientific discovery.


  • A minimum of a Ph.D. in Virology, Biochemistry, Cell Biology, Molecular Biology, Biomedical Engineering, or related discipline is required.
  • A minimum of 10 years of relevant post-graduate industry or academic experience is required.
  • Deep biological expertise in one or more eukaryotic viral vectors, including Adenovirus, adeno-associated virus (AAV), Lentivirus, and Herpes Virus, is required.
  • Experience re-engineering viruses to change their potency, serotype, replicative properties, or packaging capacity is required.
  • Experience engineering virus packaging cell lines or inducible virus-producer cell lines is preferred.
  • Experience with AAV Gene Therapy vector construction and manufacturing is preferred.
  • People management experience is required.
  • A Strong track record of scientific accomplishments directed towards discovery and development of therapeutic agents, including peer-reviewed first-author publications, patent applications, and/or presentations at major national meetings and participation in professional societies, is required.
  • Must have excellent written and oral communication skills.
  • Must have strong time management, record keeping and data analysis skills.
  • Must have demonstrated leadership skills to develop and mentor others, and to oversee and guide the work of colleagues to achieve meaningful outcomes and to create business impact.
  • The ability to collaborate with all levels and influence decision-making across a matrix organization is required.
  • This position will require up to 10% travel.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.