BioAge Labs is a venture-backed biopharmaceutical company headquartered in Richmond, CA (relocating headquarters to Emeryville, CA by April 2025). Because aging is the driver of many highly morbid, chronic medical conditions that reduce the length and quality of life, we are developing therapeutics that target the fundamental mechanisms of aging, with the goal of treating disease and increasing healthy lifespan.

We are seeking a highly motivated professional to join our team as an In Vivo Biology Scientist to conduct preclinical research for drug discovery.

Role Overview: This is a unique opportunity to be part of a rapidly growing company developing a pipeline of therapies with the potential to enhance health span and lifespan in an aging population.

Key Responsibilities

• Perform BioAge’s internal preclinical aging assays using our frailty validation platform.
• Develop high quality and reproducible animal models for efficacy and mechanism of action studies for small molecule and biologic therapeutics, in close collaboration with therapeutic area teams, pharmacology, medicinal chemistry, preclinical safety, DMPK, etc
• Perform Hands-on properly controlled experiments that generate high quality data; In-vivo technical skills, such as dosing of test substances (IP/IV/PO/SC/IM/IT/IN, etc), bleeding (submandibular/tail vein/cardiac), performing euthanasia and necropsy of laboratory mice, as necessary.
• Conduct survival surgeries to establish various rodent models using aseptic techniques; experience in ocular diseases, myopathies and metabolic diseases desired.
• Maintain detailed records of measurements, observations, and other required data of various models.
• Responsible for data review, analysis, and interpretation from a variety of sources to enable program go/no-go decisions.
• Demonstrate the ability to manage multiple in vivo experiments simultaneously.
• Closely follow study designs and IACUC protocols. Manage and observe animals for general health and overall wellbeing, maintain a clean and safe vivarium environment.
• Working together in a team environment towards the goals of our therapeutics programs.

Qualifications

• PhD with at least 2 years of in vivo biology experience in drug discovery, or BS with 10 years or MS with 5 years of hands-on in vivo biology experience will be required.
• Strong understanding of development of animal models and general physiology in a drug discovery setting.
• Excellent hands-on in-vivo technical skills are necessary.
• Highly organized and detail oriented and able to work both independently and as part of a team.
• Experience in data analysis and visualization with Excel and Prism and presentation to a cross-functional team.
• Excellent communicator with exceptional verbal, presentation, and written communication skills.
• Excellent working ability across a highly matrixed environment.
• Expertise in ocular diseases, myopathies, metabolic diseases, or age-related diseases in animal models preferred.

Our company

BioAge is a platform-driven, clinical-stage biotechnology company that is mapping human longevity to change the nature of aging and extend healthy lifespan. Our growing portfolio of therapeutics for immune, muscle, and brain aging includes four drug programs, two first-in-class and two first-in-indication. Our vision is “growing older without aging” - a future in which aging allows us to pursue our goals, accumulate new experiences and accomplishments, and actively contribute to society without disease, physical disability, or loss of independence and connection. A leading company in the emerging longevity biotech sector, BioAge has raised more than $300 million from a top-tier syndicate of investors and pharma companies.

Our workplace

BioAge offers competitive salary, a comprehensive compensation package, and generous paid time off in addition to company-observed holidays. We provide comprehensive health and wellness benefits (medical, dental, and vision insurance) and a 401(k) retirement savings plan with matching employer contributions, and we support families through childcare and fertility benefits. We also pride ourselves in giving employees many opportunities for career development, including a generous annual budget for continued learning and a dedication to training and skill development. This position is onsite Monday through Friday. The salary for this role is expected to be approximately $125,000 - $135,000 for someone who meets all of the minimum qualifications as listed for the role of Scientist I, and may be adjusted accordingly for someone with more or less experience. We are open to the concept that different experience levels add value to the team in different ways, and therefore will consider a variety of experience and offer commensurate pay.

At BioAge, we embrace diversity and differences while we learn from each other, and we believe that every team member has an important role to play. We are an equal opportunity employer. BioAge prohibits discrimination and harassment of any type and affords equal employment opportunities to employees and applicants without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. BioAge conforms to the spirit as well as to the letter of all applicable laws and regulations.