Member of Technical Staff, Epigenetics

LatchBio

LatchBio

IT

San Francisco, CA, USA

USD 180k+ / year + Equity

Posted on Jun 3, 2026

Location

San Francisco

Employment Type

Full time

Location Type

On-site

Department

Bioinformatics

As molecular data generation and frontier model intelligence grows, new approaches to data analysis are needed across the biotech industry. Latch is building intelligent, high performance agents for biological data analysis, empowering over 5,000 scientists across 150+ R&D labs to handle data from instrument-to-insights.

We're seeking a Member of Technical Staff for Epigenetics to lead our epigenomics bench, pushing its capabilities to the frontier of what artificial intelligence can achieve in biology.

About the Role

You will design our technical approach to teaching agents how to understand and handle complex epigenomics data, mapping out end-to-end data analysis workflows and working from instrument outputs to real scientific decisions.

You will lead a team of software engineers and biologists building datasets to teach these agents to reason better across:

  • Sequencing QC → alignment & peak calling

  • Chromatin accessibility analysis

  • TF footprinting & motif analysis

  • Histone modification → single-cell multiome integration

  • Gene regulatory network construction

Requirements

  • 5+ years hands-on experience with epigenetics or epigenomics data

  • Prior contribution to a novel epigenomics method, tool, or published pipeline

  • Proficiency in Python and/or R

Compensation & Logistics

  • $180k+ base, increasing with technical depth and experience

  • Variable compensation + equity + stock options

  • 100% premium covered Blue Shield platinum health plan ($0 deductible / $0 out-of-pocket)

  • Free meals (lunch and dinner)

  • Waterfront office in China Basin, San Francisco

  • Full-time, in-person

Location: San Francisco, CA. In-person.