Recursion Pharmaceuticals is at the forefront of the integration of data, AI, and an industrialized approach to significantly reduce costs, accelerate timelines, and increase the likelihood of success in developing new medicines. We are seeking a DMPK project representative to drive both internal and partnership projects in drug discovery and early development. You will provide expert DMPK guidance for projects from hit identification, hit-to-lead, lead optimization, candidate profiling, to IND and beyond. As a DMPK project representative, you will:

Collaborate closely with project teams to resolve ADME/PK challenges, facilitating the discovery and development of high-quality clinical candidates
Drive project progression from initial discovery through clinical development, playing a key role in Recursion’s scientific and strategic initiatives
Partner with AI and machine learning experts to develop and leverage state of the art predictive and computational tools to expedite ADME/PK property optimization efforts
Collaborate with project teams to define and execute DMPK strategy, producing comprehensive IND-enabling data packages including translational plans, human dose projections, DDI liability assessments, and input for Phase 1 clinical design
Support and mentor junior scientists on project teams and within DMPK

The Team You’ll Join

You will join the DMPK team, a comprehensive end-to-end organization dedicated to influencing every phase of drug discovery and development. The team is committed to leveraging translational strategies early in discovery projects to accelerate candidate selection and clinical development. You will work closely with colleagues in Medicinal Chemistry, Pharmacology, Biology, Clinical Pharmacology, Toxicology, data scientists and others.

The Experience You’ll Need

PhD or PharmD with 5+ years of experience as a DMPK project representative or subject matter expert in drug discovery and development, or MS with 7+ years of experience in drug discovery and development within the biotech or pharmaceutical industry
In-depth experience as a DMPK project representative across key stages of drug discovery and development, including hit-to-lead, lead optimization, candidate selection, IND/IB preparation, and early clinical development
Extensive and broad expertise in ADME assays, pharmacokinetics (PK), drug–drug interactions (DDI, TDI, induction), clearance mechanisms (metabolism, renal, biliary), drug-metabolizing enzymes, transporters, oral absorption, disposition, human PK and dose prediction, as well as PK/PD and PBPK modeling and simulations
Utilize modeling and simulation tools, as well as in silico ADME models, to guide compound prioritization, optimization, and project advancement
Experience preparing regulatory submissions (e.g., INDs, Investigator’s Brochures) and addressing regulatory agency inquiries
Strong analytical, troubleshooting, and organizational skills applied within fast-paced project teams to accelerate the progression of drug discovery programs
Proven track record of effective collaboration and communication with cross-functional teams
Demonstrated experience mentoring and guiding others

How You’ll be Supported

Training on Recursion’s culture and values and our Drug Discovery & Development processes to provide insight into our unique approach and strategy for success.
Frequent, direct engagement with peers and leaders within DMPK and across functions to support your ongoing growth and learning
Opportunity to learn and use AI/ML models for ADME/PK prediction
Professional development is fostered through comprehensive in-house learning opportunities and support for attending industry conferences relevant to your expertise

Working Location & Compensation

This is an office-based, hybrid role in our New York City, NY office. Employees are expected to work in the office at least 50% of the time. At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is: $195,700 - $256,500.

You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.

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The Values We Hope You Share:

We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust.
We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action.
We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection.
We move with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day.
We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy—leaders take accountability for decisive action, and teams own outcomes together.
We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities.

Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively.

More About Recursion

Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously generate one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.

Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in Toronto, Montréal, New York, London, Oxford area, and the San Francisco Bay area. Learn more at www.Recursion.com, or connect on X (formerly Twitter) and LinkedIn.

Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.

Accommodations are available on request for candidates taking part in all aspects of the selection process.