Scientist / Sr. Scientist, Medical Hibernation
Until
San Francisco, CA, USA
Posted on Sep 26, 2025
Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.
To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.
We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.
About the Role
We are seeking a Scientist / Senior Scientist to establish and lead advanced in-vivo and ex-vivo heart evaluation platforms. In this role, you will design and implement assays to assess cardiac viability, identify sources of chemical toxicity or mechanical injury, and integrate diverse evaluation data. Working closely with our team, you will provide critical insights to refine our whole-body cryoprotectant perfusion system and enable recovery of functional heart outputs.
Key Responsibilities
- Establish platforms to assess rodent heart functionally (ECG, echocardiograph) and structurally.
- Capable of integrating heart structure and function data output to pinpoint chemical toxicity or mechanical injury mechanisms.
- Developed assays / experiments to test out chemical toxicity or mechanical injury hypothesis.
- Work with our team to optimize the current perfusion protocol.
Qualifications
- You’ve completed an MD or PhD.
- Expertise in heart function assessment.
- Exhibited agency and rapid problem-solving capability.
- Demonstrated the passion to implement creative and novel approaches to solve multifaceted problems as they arise.
What We Offer
- Opportunity for outsized impact creating the future as an early team member
- Generous medical, dental and vision insurance coverage
- Flexible time off and paid holidays
- Competitive compensation package, including salary and equity
- 401(k) retirement savings plan
- FSA and commuter benefits
- Subsidized lunch daily
As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.